CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.170 | Beta Complex |
|
2.170.270 | Beta-clip-like |
|
2.170.270.10 | SET domain |
Domain Context
CATH Clusters
| Superfamily | SET domain |
| Functional Family | Putative histone-lysine n-methyltransferase prdm9 |
Enzyme Information
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q96EQ9
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (2)
| Q96EQ9 |
PRDM9_MOUSE
Mus musculus
Histone-lysine N-methyltransferase PRDM9
|
| P68431 |
H31_HUMAN
Homo sapiens
Histone H3.1
|
PDB Structure
| PDB | 4C1Q |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of Prdm9.
Cell Rep.
|