CATH Classification

Domain Context

CATH Clusters

Superfamily Golgi alpha-mannosidase II
Functional Family Starch branching enzyme 1

Enzyme Information

2.4.1.18
1,4-alpha-glucan branching enzyme.
based on mapping to UniProt Q04446
Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.
-!- Converts amylose into amylopectin. -!- The description (official name) requires a qualification depending on the product, glycogen or amylopectin, e.g. glycogen branching enzyme, amylopectin branching enzyme. -!- The latter has frequently been termed Q-enzyme.

UniProtKB Entries (1)

Q04446
GLGB_HUMAN
Homo sapiens
1,4-alpha-glucan-branching enzyme

PDB Structure

PDB 4BZY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Glycogen Branching Enzyme Deficiency and Pharmacologic Rescue by Rational Peptide Design.
Froese, D.S., Michaeli, A., Mccorvie, T.J., Krojer, T., Sasi, M., Melaev, E., Goldblum, A., Zatsepin, M., Lossos, A., Alvarez, R., Escriba, P.V., Minaissan, B.A., von Delft, F., Kakhlon, O., Yue, W.W.
Hum.Mol.Genet.