CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family UDP-N-acetylmuramoylalanine--D-glutamate ligase

Enzyme Information

6.3.2.9
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.
based on mapping to UniProt Q9WY76
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate.
-!- Involved in the synthesis of a cell-wall peptide in bacteria.

UniProtKB Entries (1)

Q9WY76
MURD_THEMA
Thermotoga maritima MSB8
UDP-N-acetylmuramoylalanine--D-glutamate ligase

PDB Structure

PDB 4BUC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mreb and Murg as Scaffolds for the Cytoplasmic Steps of Peptidoglycan Biosynthesis
Favini-Stabile, S., Contreras-Martel, C., Thielens, N., Dessen, A.
Environ.Microbiol.