CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.220 | Leucine Aminopeptidase, subunit E; domain 1 |
|
3.40.220.10 | Leucine Aminopeptidase, subunit E, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Leucine Aminopeptidase, subunit E, domain 1 |
| Functional Family | Poly [ADP-ribose] polymerase 15 |
Enzyme Information
| 2.4.2.30 |
NAD(+) ADP-ribosyltransferase.
based on mapping to UniProt Q460N3
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D- ribosyl)(n+1)-acceptor.
-!- The ADP-D-ribosyl group of NAD(+) is transferred to an acceptor carboxy group on a histone or the enzyme itself, and further ADP- ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.
|
UniProtKB Entries (1)
| Q460N3 |
PAR15_HUMAN
Homo sapiens
Poly [ADP-ribose] polymerase 15
|
PDB Structure
| PDB | 3V2B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.
Structure
|