CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Somatic embryogenesis receptor kinase 2

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q94F62
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt Q94F62
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (2)

Q8RSY1
HPAB2_PSESM
[Pseudomonas syringae] pv. tomato str. DC3000
Effector protein HopAB2
Q94F62
BAK1_ARATH
Arabidopsis thaliana
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1

PDB Structure

PDB 3TL8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of Pseudomonas syringae AvrPtoB Bound to Host BAK1 Reveals Two Similar Kinase-Interacting Domains in a Type III Effector.
Cheng, W., Munkvold, K.R., Gao, H., Mathieu, J., Schwizer, S., Wang, S., Yan, Y.B., Wang, J., Martin, G.B., Chai, J.
Cell Host Microbe