CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Mycinamicin VI 2''-O-methyltransferase |
Enzyme Information
| 2.1.1.238 |
Mycinamicin VI 2''-O-methyltransferase.
based on mapping to UniProt Q83WF2
S-adenosyl-L-methionine + mycinamicin VI = S-adenosyl-L-homocysteine + mycinamicin III.
-!- The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics. -!- Requires Mg(2+) for optimal activity.
|
UniProtKB Entries (1)
| Q83WF2 |
MYCE_MICGR
Micromonospora griseorubida
Mycinamicin VI 2''-O-methyltransferase
|
PDB Structure
| PDB | 3SSM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol.
|