CATH Domain 3s8sA00

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.330	RRM (RNA recognition motif) domain

Superfamily	3.30.70.330
Functional Family	Histone-lysine N-methyltransferase SETD1A

2.1.1.43

Histone-lysine N-methyltransferase.

based on mapping to UniProt O15047

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

SET1A_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase SETD1A

PDB	3S8S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of the RRM domain of human SETD1A Chao, X., Tempel, W., Bian, C., Cerovina, T., Walker, J.R., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J. to be published