CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family ATP-dependent DNA helicase RuvB

Enzyme Information
DNA helicase.
based on mapping to UniProt Q9PMT7
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC (RNA helicase).

UniProtKB Entries (1)

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Holliday junction ATP-dependent DNA helicase RuvB

PDB Structure

External Links
Primary Citation
2.7 Angstrom resolution crystal structure of a probable holliday junction DNA helicase (ruvB) from Campylobacter jejuni subsp. jejuni NCTC 11168 in complex with adenosine-5'-diphosphate
Halavaty, A.S., Wawrzak, Z., Skarina, T., Onopriyenko, O., Edwards, A., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published