CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.79 | Nucleoside Triphosphate Pyrophosphohydrolase |
|
3.90.79.10 | Nucleoside Triphosphate Pyrophosphohydrolase |
Domain Context
CATH Clusters
| Superfamily | Nucleoside Triphosphate Pyrophosphohydrolase |
| Functional Family | Nucleoside triphosphatase NudI |
Enzyme Information
| 3.6.1.9 |
Nucleotide diphosphatase.
based on mapping to UniProt Q8ZNF5
A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate.
-!- The enzyme preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates. -!- In vitro the enzyme also acts as a nucleotidohydrolase on ADP, NAD(+), NADP(+), FAD, and CoA. -!- Formerly EC 3.6.1.19.
|
| 3.6.1.- |
In phosphorus-containing anhydrides.
based on mapping to UniProt Q8ZNF5
|
| 3.6.1.12 |
dCTP diphosphatase.
based on mapping to UniProt Q8ZNF5
dCTP + H(2)O = dCMP + diphosphate.
-!- Also hydrolyzes dCDP to dCMP and phosphate.
|
| 3.6.1.23 |
dUTP diphosphatase.
based on mapping to UniProt Q8ZNF5
dUTP + H(2)O = dUMP + diphosphate.
|
UniProtKB Entries (1)
| Q8ZNF5 |
NUDI_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Nucleoside triphosphatase NudI
|
PDB Structure
| PDB | 3N77 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2
To be Published
|