CATH Domain 3n5nX02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.340	Endonuclease III; domain 1
	1.10.340.30	Hypothetical protein; domain 2

Domain Context

CATH Clusters

Superfamily	Hypothetical protein; domain 2
Functional Family	A/G-specific adenine DNA glycosylase

Enzyme Information

3.2.2.-

Hydrolyzing N-glycosyl compounds.

based on mapping to UniProt Q9UIF7

UniProtKB Entries (1)

MUTYH_HUMAN

Homo sapiens

Adenine DNA glycosylase

PDB Structure

PDB	3N5N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. Luncsford, P.J., Chang, D.Y., Shi, G., Bernstein, J., Madabushi, A., Patterson, D.N., Lu, A.L., Toth, E.A. J.Mol.Biol.