CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family Serine hydroxymethyltransferase

Enzyme Information

2.1.2.1
Glycine hydroxymethyltransferase.
based on mapping to UniProt P24531
5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.
-!- Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine.

UniProtKB Entries (1)

P24531
GLYA_CAMJE
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Serine hydroxymethyltransferase

PDB Structure

PDB 3N0L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of serine hydroxymethyltransferase from Campylobacter jejuni
Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Hasseman, J., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
TO BE PUBLISHED