CATH Domain 3n0lA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.1150	Aspartate Aminotransferase, domain 1
	3.90.1150.10	Aspartate Aminotransferase, domain 1

Domain Context

CATH Clusters

Superfamily	Aspartate Aminotransferase, domain 1
Functional Family	Serine hydroxymethyltransferase

Enzyme Information

2.1.2.1

Glycine hydroxymethyltransferase.

based on mapping to UniProt P24531

5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.

-!- Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine.

UniProtKB Entries (1)

P24531

GLYA_CAMJE

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Serine hydroxymethyltransferase

PDB Structure

PDB	3N0L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of serine hydroxymethyltransferase from Campylobacter jejuni Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Hasseman, J., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID) TO BE PUBLISHED