CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Putative 3-oxoacyl-[acyl-carrier protein] reductase FabG4 |
Enzyme Information
| 1.1.1.100 |
3-oxoacyl-[acyl-carrier-protein] reductase.
based on mapping to UniProt O53665
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
-!- Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates.
|
UniProtKB Entries (1)
| O53665 |
O53665_MYCTO
Mycobacterium tuberculosis CDC1551
3-oxoacyl-(Acyl-carrier-protein) reductase
|
PDB Structure
| PDB | 3M1L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of FabG4 from Mycobacterium tuberculosis reveals the importance of C-terminal residues in ketoreductase activity
J.Struct.Biol.
|