CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha-ketoglutarate-dependent dioxygenase AlkB-like
Functional Family Alpha-ketoglutarate-dependent dioxygenase FTO

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q9C0B1

UniProtKB Entries (1)

Q9C0B1
FTO_HUMAN
Homo sapiens
Alpha-ketoglutarate-dependent dioxygenase FTO

PDB Structure

PDB 3LFM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the FTO protein reveals basis for its substrate specificity
Han, Z., Niu, T., Chang, J., Lei, X., Zhao, M., Wang, Q., Cheng, W., Wang, J., Feng, Y., Chai, J.
Nature