CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1370 | Aspartate/ornithine carbamoyltransferase |
Domain Context
CATH Clusters
| Superfamily | Aspartate/ornithine carbamoyltransferase |
| Functional Family | Complete genome, strain B100 |
Enzyme Information
| 2.1.3.3 |
Ornithine carbamoyltransferase.
based on mapping to UniProt Q8P8J2
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
-!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.
|
| 2.1.3.9 |
N-acetylornithine carbamoyltransferase.
based on mapping to UniProt Q8P8J2
Carbamoyl phosphate + N(2)-acetyl-L-ornithine = phosphate + N-acetyl-L- citrulline.
-!- Differs from EC 2.1.3.3. -!- This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate.
|
UniProtKB Entries (1)
| Q8P8J2 |
AOTC_XANCP
Xanthomonas campestris pv. campestris str. ATCC 33913
N-acetylornithine carbamoyltransferase
|
PDB Structure
| PDB | 3KZC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria.
J.Biol.Chem.
|