CATH Domain 3k2iA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1820	Alpha/Beta hydrolase fold, catalytic domain

Domain Context

CATH Clusters

Superfamily	3.40.50.1820
Functional Family	Acyl-coenzyme A thioesterase 1

Enzyme Information

3.1.2.2

Palmitoyl-CoA hydrolase.

based on mapping to UniProt Q8N9L9

Palmitoyl-CoA + H(2)O = CoA + palmitate.

-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.

UniProtKB Entries (1)

ACOT4_HUMAN

Homo sapiens

Acyl-coenzyme A thioesterase 4

PDB Structure

PDB	3K2I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Human Acyl-coenzyme A thioesterase 4 Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H. To be Published