CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Formate dehydrogenase 2, mitochondrial

Enzyme Information

1.2.1.2
Formate dehydrogenase.
based on mapping to UniProt Q9S7E4
Formate + NAD(+) = CO(2) + NADH.
-!- The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center. -!- Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.

UniProtKB Entries (1)

Q9S7E4
FDH_ARATH
Arabidopsis thaliana
Formate dehydrogenase, chloroplastic/mitochondrial

PDB Structure

PDB 3JTM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of recombinant formate dehydrogenase from Arabidopsis thaliana
Timofeev, V.I., Shabalin, I.G., Serov, A.E., Polyakov, K.M., Popov, V.O., Tishkov, V.I., Kuranova, I.P., Samigina, V.R.
to be published