CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Valine--pyruvate aminotransferase |
Enzyme Information
| 2.6.1.1 |
Aspartate transaminase.
based on mapping to UniProt Q8ZL86
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.
|
| 2.6.1.66 |
Valine--pyruvate transaminase.
based on mapping to UniProt Q8ZL86
L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.
-!- Different from EC 2.6.1.42.
|
UniProtKB Entries (1)
| Q8ZL86 |
Q8ZL86_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Valine-pyruvate aminotransferase
|
PDB Structure
| PDB | 3G7Q |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of valine-pyruvate aminotransferase AvtA (NP_462565.1) from Salmonella typhimurium LT2 at 1.80 A resolution
To be published
|
