CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | Alpha/Beta hydrolase fold, catalytic domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.1820 |
| Functional Family | S-formylglutathione hydrolase FrmB |
Enzyme Information
| 3.1.2.12 |
S-formylglutathione hydrolase.
based on mapping to UniProt P10768
S-formylglutathione + H(2)O = glutathione + formate.
-!- Also hydrolyzes S-acetylglutathione, more slowly.
|
| 3.1.1.56 |
Methylumbelliferyl-acetate deacetylase.
based on mapping to UniProt P10768
4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate.
-!- Acts on short-chain acyl esters of 4-methylumbelliferone, but not on naphthyl, indoxyl or thiocholine esters.
|
UniProtKB Entries (1)
| P10768 |
ESTD_HUMAN
Homo sapiens
S-formylglutathione hydrolase
|
PDB Structure
| PDB | 3FCX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of human esterase D: a potential genetic marker of retinoblastoma
Faseb J.
|