CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.360
Functional Family Glutathione-regulated potassium-efflux system ancillary protein

Enzyme Information

1.6.5.2
NAD(P)H dehydrogenase (quinone).
based on mapping to UniProt P0A754
NAD(P)H + a quinone = NAD(P)(+) + a hydroquinone.
-!- The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone. -!- The animal, but not the plant, form of the enzyme is inhibited by dicoumarol. -!- Formerly EC 1.6.99.2.

UniProtKB Entries (1)

P03819
KEFC_ECOLI
Escherichia coli K-12
Glutathione-regulated potassium-efflux system protein KefC

PDB Structure

PDB 3EYW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
KTN (RCK) Domains Regulate K(+) Channels and Transporters by Controlling the Dimer-Hinge Conformation.
Roosild, T.P., Castronovo, S., Miller, S., Li, C., Rasmussen, T., Bartlett, W., Gunasekera, B., Choe, S., Booth, I.R.
Structure