CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.450 | Nuclear Transport Factor 2; Chain: A, |
|
3.10.450.50 |
Domain Context
CATH Clusters
| Superfamily | 3.10.450.50 |
| Functional Family | Benzoate 1,2-dioxygenase subunit beta |
Enzyme Information
| 1.14.12.10 |
Benzoate 1,2-dioxygenase.
based on mapping to UniProt A0A0H2WBM4
Benzoate + NADH + O(2) = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1- carboxylate + NAD(+).
-!- A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), and an iron-sulfur oxygenase. -!- Formerly EC 1.13.99.2.
|
| 1.14.12.13 |
2-halobenzoate 1,2-dioxygenase.
based on mapping to UniProt A0A0H2WBM4
A 2-halobenzoate + NADH + O(2) = catechol + a halide anion + NAD(+) + CO(2).
-!- A multicomponent enzyme system composed of a dioxygenase component and an electron transfer component. -!- The latter contains FAD. -!- The enzyme, characterized from the bacterium Burkholderia cepacia 2CBS, has a broad substrate specificity. -!- Substrates include 2-fluorobenzoate, 2-chlorobenzoate, 2-bromobenzoate, and 2-iodobenzoate, which are processed in this order of preference.
|
UniProtKB Entries (1)
| A0A0H2WBM4 |
A0A0H2WBM4_BURMA
Burkholderia mallei ATCC 23344
Benzoate 1,2-dioxygenase beta subunit
|
PDB Structure
| PDB | 3E99 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the beta subunit of benzoate 1,2-dioxygenase (YP_105014.1) from BURKHOLDERIA MALLEI ATCC 23344 at 1.90 A resolution
To be published
|