CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family tRNA (Guanine-N(7)-)-methyltransferase (Modular protein)

Enzyme Information

2.1.1.33
tRNA (guanine(46)-N(7))-methyltransferase.
based on mapping to UniProt P0A8I5
S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.
-!- The enzyme specifically methylates guanine(46) at N(7) in tRNA.

UniProtKB Entries (1)

P0A8I5
TRMB_ECOLI
Escherichia coli K-12
TRNA (guanine-N(7)-)-methyltransferase

PDB Structure

PDB 3DXX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Zhou, H., Liu, Q., Yang, W., Gao, Y., Teng, M., Niu, L.
Proteins