CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.830 | Cytochrome Bc1 Complex; Chain A, domain 1 | |
3.30.830.10 | Metalloenzyme, LuxS/M16 peptidase-like |
Domain Context
CATH Clusters
Superfamily | Metalloenzyme, LuxS/M16 peptidase-like |
Functional Family | Cytochrome b-c1 complex subunit 2, mitochondrial |
Enzyme Information
1.10.2.2 |
Quinol--cytochrome-c reductase.
based on mapping to UniProt D0VX29
Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H(+).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and C(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3).
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UniProtKB Entries (1)
Q5ZLR5 |
UCRI_CHICK
Gallus gallus
Cytochrome b-c1 complex subunit Rieske, mitochondrial
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PDB Structure
PDB | 3CWB |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D.
Bioorg.Med.Chem.
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