CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family 2,4-dihydroxyacetophenone dioxygenase

Enzyme Information

1.13.11.50
Acetylacetone-cleaving enzyme.
based on mapping to UniProt Q8GNT2
Pentane-2,4-dione + O(2) = acetate + 2-oxopropanal.
-!- Forms the first step in the acetylacetone degradation pathway of Acinetobacter johnsonii. -!- While acetylacetone is by far the best substrate, heptane-3,5-dione, octane-2,4-dione, 2-acetylcyclohexanone and ethyl acetoacetate can also act as substrates.

UniProtKB Entries (1)

Q8GNT2
DKE1_ACIJO
Acinetobacter johnsonii
Acetylacetone-cleaving enzyme

PDB Structure

PDB 3BAL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of an Acetylacetone Dioxygenase from Acinetobacter johnsonii
Stranzl, G.R., Wagner, U.G., Straganz, G., Steiner, W., Kratky, C.
To be Published