CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.237
Hydroxyphenylpyruvate reductase.
based on mapping to UniProt Q65CJ7
3-(4-hydroxyphenyl)lactate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + NADH.
-!- Also acts on 3-(3,4-dihydroxyphenyl)lactate. -!- Involved with EC 2.3.1.140 in the biosynthesis of rosmarinic acid.

UniProtKB Entries (1)

Q65CJ7
HPPR_PLESU
Solenostemon scutellarioides
Hydroxyphenylpyruvate reductase

PDB Structure

PDB 3BA1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth.
Janiak, V., Petersen, M., Zentgraf, M., Klebe, G., Heine, A.
Acta Crystallogr.,Sect.D