CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family Probable betaine aldehyde dehydrogenase

Enzyme Information

1.2.1.3
Aldehyde dehydrogenase (NAD(+)).
based on mapping to UniProt P96405
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
-!- Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. -!- Formerly EC 1.1.1.70.
1.2.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt P96405

UniProtKB Entries (1)

P96405
P96405_MYCTO
Mycobacterium tuberculosis CDC1551
Aldehyde dehydrogenase family protein

PDB Structure

PDB 3B4W
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-ray crystal structure of aldehyde dehydrogenase from Mycobacterium tuberculosis complexed with NAD+.
Moon, J.H., Lyon, A.E., Yu, M., Hung, L.-W., Terwilliger, T., Kim, C.-Y.
To Be Published