1 keywords

CATH Domain 2xr9A03

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.720 Alkaline Phosphatase, subunit A
Homologous Superfamily 3.40.720.10 Alkaline Phosphatase, subunit A

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Ectonucleotide pyrophosphatase/phosphodiesterase 3 (Predicted)

Enzyme Information

3.1.4.39
Alkylglycerophosphoethanolamine phosphodiesterase.
based on mapping to UniProt Q64610
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.
-!- Also acts on acyl and choline analogs.

UniProtKB Entries (1)

Q64610
ENPP2_RAT
Rattus norvegicus
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

PDB Structure

PDB 2XR9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of substrate discrimination and integrin binding by autotaxin.
Hausmann, J., Kamtekar, S., Christodoulou, E., Day, J.E., Wu, T., Fulkerson, Z., Albers, H.M., van Meeteren, L.A., Houben, A.J., van Zeijl, L., Jansen, S., Andries, M., Hall, T., Pegg, L.E., Benson, T.E., Kasiem, M., Harlos, K., Kooi, C.W., Smyth, S.S., Ovaa, H., Bollen, M., Morris, A.J., Moolenaar, W.H., Perrakis, A.
Nat. Struct. Mol. Biol.