CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.860 | DNAb Helicase; Chain A | |
1.10.860.10 | DNAb Helicase; Chain A |
Domain Context
CATH Clusters
Superfamily | DNAb Helicase; Chain A |
Functional Family | Replicative DNA helicase |
Enzyme Information
3.6.4.12 |
DNA helicase.
based on mapping to UniProt Q5KU75
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
Q5KU75 |
Q5KU75_GEOKA
Geobacillus kaustophilus HTA426
Replicative DNA helicase
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PDB Structure
PDB | 2VYF |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The Crystal Structure of a Replicative Hexameric Helicase Dnac and its Complex with Single-Stranded DNA.
Nucleic Acids Res.
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