CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Calcium/calmodulin-dependent protein kinase type II

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q13555
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q13555
KCC2G_HUMAN
Homo sapiens
Calcium/calmodulin-dependent protein kinase type II subunit gamma

PDB Structure

PDB 2V7O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.
Rellos, P., Pike, A.C.W., Niesen, F.H., Salah, E., Lee, W.H., von Delft, F., Knapp, S.
Plos Biol.