CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Methyltransferase domain protein

Enzyme Information

3.4.24.71
Endothelin-converting enzyme 1.
based on mapping to UniProt O60344
Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form endothelin 1.
-!- Phosphoramidon-sensitive. -!- Belongs to peptidase family M13.
2.1.1.-
Methyltransferases.
based on mapping to UniProt O60344

UniProtKB Entries (1)

O60344
ECE2_HUMAN
Homo sapiens
Endothelin-converting enzyme 2

PDB Structure

PDB 2PXX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene.
Tempel, W., Wu, H., Dombrovsky, L., Zeng, H., Loppnau, P., Zhu, H., Plotnikov, A.N., Bochkarev, A.
Proteins