CATH Classification

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family UDP-glucuronosyltransferase 2B1-like isoform 1

Enzyme Information

2.4.1.17
Glucuronosyltransferase.
based on mapping to UniProt P16662
UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
-!- Family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines and fatty acids. -!- Some of the activities catalyzed were previously listed separately as EC 2.4.1.42, EC 2.4.1.59, EC 2.4.1.61, EC 2.4.1.76, EC 2.4.1.77, EC 2.4.1.84, EC 2.4.1.107 and EC 2.4.1.108.

UniProtKB Entries (1)

P16662
UD2B7_HUMAN
Homo sapiens
UDP-glucuronosyltransferase 2B7

PDB Structure

PDB 2O6L
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7.
Miley, M.J., Zielinska, A.K., Keenan, J.E., Bratton, S.M., Radominska-Pandya, A., Redinbo, M.R.
J.Mol.Biol.