CATH Classification

Domain Context

CATH Clusters

Superfamily Blc2-like
Functional Family Myeloid cell leukemia ES variant

Enzyme Information

UniProtKB Entries (2)

Q9JM54
APR_MOUSE
Mus musculus
Phorbol-12-myristate-13-acetate-induced protein 1
Q07820
MCL1_HUMAN
Homo sapiens
Induced myeloid leukemia cell differentiation protein Mcl-1

PDB Structure

PDB 2NLA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural insights into the degradation of Mcl-1 induced by BH3 domains.
Czabotar, P.E., Lee, E.F., van Delft, M.F., Day, C.L., Smith, B.J., Huang, D.C., Fairlie, W.D., Hinds, M.G., Colman, P.M.
Proc.Natl.Acad.Sci.USA