CATH Classification

Domain Context

CATH Clusters

Superfamily Helix-loop-helix DNA-binding domain
Functional Family Transcription factor hes-1, putative

Enzyme Information

UniProtKB Entries (1)

Q14469
HES1_HUMAN
Homo sapiens
Transcription factor HES-1

PDB Structure

PDB 2MH3
External Links
Method SOLUTION NMR
Organism
Primary Citation
The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA.
Popovic, M., Wienk, H., Coglievina, M., Boelens, R., Pongor, S., Pintar, A.
Proteins