CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.260
Functional Family Acetolactate synthase small subunit

Enzyme Information

2.2.1.6
Acetolactate synthase.
based on mapping to UniProt P0ADF8
2 pyruvate = 2-acetolactate + CO(2).
-!- The reaction shown is in the pathway of biosynthesis of valine. -!- The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine. -!- Formerly EC 4.1.3.18.
4.1.3.18
Transferred entry: 2.2.1.6.
based on mapping to UniProt P0ADF8

UniProtKB Entries (1)

P0ADF8
ILVN_ECOLI
Escherichia coli K-12
Acetolactate synthase isozyme 1 small subunit

PDB Structure

PDB 2LVW
External Links
Method SOLUTION NMR
Organism
Primary Citation
The coil-to-helix transition in IlvN regulates the allosteric control of Escherichia coli acetohydroxyacid synthase I
Karanth, N.M., Sarma, S.P.
Biochemistry