CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.102 | 3-layer Sandwich | |
2.102.10 | Rieske Iron-sulfur Protein | |
2.102.10.10 | Rieske [2Fe-2S] iron-sulphur domain |
Domain Context
CATH Clusters
Superfamily | Rieske [2Fe-2S] iron-sulphur domain |
Functional Family | Nitrite reductase small subunit |
Enzyme Information
1.7.1.4 |
Nitrite reductase (NAD(P)H).
based on mapping to UniProt P0A9I8
Ammonia + 3 NAD(P)(+) + 2 H(2)O = nitrite + 3 NAD(P)H.
-!- The enzymes from the fungi Neurospora crassa, Emericella nidulans and Candida nitratophila and the bacterium Aliivibrio fischeri can use either NADPH or NADH as electron donor. -!- Cf. EC 1.7.1.15. -!- Formerly EC 1.6.6.4.
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1.6.6.4 |
Transferred entry: 1.7.1.4.
based on mapping to UniProt P0A9I8
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1.7.1.15 |
Nitrite reductase (NADH).
based on mapping to UniProt P0A9I8
Ammonia + 3 NAD(+) + 2 H(2)O = nitrite + 3 NADH.
-!- This prokaryotic enzyme is specific for NADH. -!- In addition to catalyzing the 6-electron reduction of nitrite to ammonia, the enzyme from Escherichia coli can also catalyze the 2-electron reduction of hydroxylamine to ammonia. -!- cf. EC 1.7.1.4.
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UniProtKB Entries (1)
P0A9I8 |
NIRD_ECOLI
Escherichia coli K-12
Nitrite reductase (NADH) small subunit
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PDB Structure
PDB | 2JO6 |
External Links | |
Method | SOLUTION NMR |
Organism | Escherichia |
Primary Citation |
NMR structure of E.coli NirD.
To be Published
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