CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.330
Functional Family Histone-lysine N-methyltransferase, H3 lysine-4 specific

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt P38827
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

P38827
SET1_YEAST
Saccharomyces cerevisiae S288C
Histone-lysine N-methyltransferase, H3 lysine-4 specific

PDB Structure

PDB 2J8A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-Ray Structure of the N-Terminus Rrm Domain of Set1
Tresaugues, L., Dehe, P.M., Guerois, R., Rodriguez-Gil, A., Varlet, I., Salah, P., Pamblanco, M., Luciano, P., Quevillon-Cheruel, S., Sollier, J., Leulliot, N., Couprie, J., Tordera, V., Zinn-Justin, S., Chavez, S., Van Tilbeurgh, H., Geli, V.
To be Published