CATH Classification

Domain Context

CATH Clusters

Superfamily Ras guanine-nucleotide exchange factors catalytic domain
Functional Family Ras guanine nucleotide exchange factor

Enzyme Information

UniProtKB Entries (1)

P27671
RGRF1_MOUSE
Mus musculus
Ras-specific guanine nucleotide-releasing factor 1

PDB Structure

PDB 2IJE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A Ras-induced conformational switch in the Ras activator Son of sevenless.
Freedman, T.S., Sondermann, H., Friedland, G.D., Kortemme, T., Bar-Sagi, D., Marqusee, S., Kuriyan, J.
Proc.Natl.Acad.Sci.Usa