CATH Domain 2iikA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.47	Peroxisomal Thiolase; Chain A, domain 1
	3.40.47.10	Thiolase/Chalcone synthase

Domain Context

CATH Clusters

Superfamily	3.40.47.10
Functional Family	3-ketoacyl-CoA thiolase A, peroxisomal

Enzyme Information

2.3.1.16

Acetyl-CoA C-acyltransferase.

based on mapping to UniProt P09110

Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.

UniProtKB Entries (1)

THIK_HUMAN

Homo sapiens

3-ketoacyl-CoA thiolase, peroxisomal

PDB Structure

PDB	2IIK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1) Papagrigoriou, E., Johansson, C., Smee, C., Kavanagh, K., Pike, A.C.W., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C.H., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC) TO BE PUBLISHED