CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Kynureninase (L-kynurenine hydrolase) variant |
Enzyme Information
| 3.7.1.3 |
Kynureninase.
based on mapping to UniProt Q16719
L-kynurenine + H(2)O = anthranilate + L-alanine.
-!- Also acts on 3'-hydroxykynurenine and some other (3-arylcarbonyl)- alanines.
|
UniProtKB Entries (1)
| Q16719 |
KYNU_HUMAN
Homo sapiens
Kynureninase
|
PDB Structure
| PDB | 2HZP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Homo sapiens Kynureninase.
Biochemistry
|