CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.640 | Aspartate Aminotransferase; domain 2 | |
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Functional Family | Serine--pyruvate aminotransferase, mitochondrial |
Enzyme Information
2.6.1.44 |
Alanine--glyoxylate transaminase.
based on mapping to UniProt Q3LSM4
L-alanine + glyoxylate = pyruvate + glycine.
-!- With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. -!- A second component also catalyzes the reaction of EC 2.6.1.51.
|
2.6.1.51 |
Serine--pyruvate transaminase.
based on mapping to UniProt Q3LSM4
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
-!- The liver enzyme may be identical with EC 2.6.1.44.
|
UniProtKB Entries (1)
Q3LSM4 |
Q3LSM4_AEDAE
Aedes aegypti
Serine--pyruvate aminotransferase
|
PDB Structure
PDB | 2HUU |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Spodoptera |
Primary Citation |
Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
J.Biol.Chem.
|