CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | Alpha/Beta hydrolase fold, catalytic domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.1820 |
| Functional Family | Triacylglycerol lipase |
Enzyme Information
| 3.1.1.3 |
Triacylglycerol lipase.
based on mapping to UniProt P04635
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
|
| 3.1.1.32 |
Phospholipase A(1).
based on mapping to UniProt P04635
Phosphatidylcholine + H(2)O = 2-acylglycerophosphocholine + a carboxylate.
-!- Has a much broader specificity than EC 3.1.1.4.
|
UniProtKB Entries (1)
| P04635 |
LIP_STAHY
Staphylococcus hyicus
Lipase
|
PDB Structure
| PDB | 2HIH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis of phospholipase activity of Staphylococcus hyicus lipase.
J.Mol.Biol.
|
