CATH Classification

Domain Context

CATH Clusters

Superfamily Chorismate mutase
Functional Family Isochorismate pyruvate-lyase [pyochelin] siderophore

Enzyme Information

5.4.99.5
Chorismate mutase.
based on mapping to UniProt Q51507
Chorismate = prephenate.
4.2.99.21
Isochorismate lyase.
based on mapping to UniProt Q51507
Isochorismate = salicylate + pyruvate.
-!- This enzyme is part of the pathway of salicylate formation from chorismate, and forms an integral part of pathways that produce salicylate-derived siderophores, such as pyochelin and yersiniabactin.

UniProtKB Entries (1)

Q51507
PCHB_PSEAE
Pseudomonas aeruginosa PAO1
Isochorismate pyruvate lyase

PDB Structure

PDB 2H9C
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Two Crystal Structures of the Isochorismate Pyruvate Lyase from Pseudomonas aeruginosa.
Zaitseva, J., Lu, J., Olechoski, K.L., Lamb, A.L.
J.Biol.Chem.