CATH Classification

Domain Context

CATH Clusters

Superfamily Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family UDP-N-acetylenolpyruvoylglucosamine reductase

Enzyme Information

1.3.1.98
UDP-N-acetylmuramate dehydrogenase.
based on mapping to UniProt Q5SJC8
UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

UniProtKB Entries (1)

Q5SJC8
MURB_THET8
Thermus thermophilus HB8
UDP-N-acetylenolpyruvoylglucosamine reductase

PDB Structure

PDB 2GQT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus
Kim, M.-K., Cho, M.K., Song, H.-E., Kim, D., Park, B.-H., Lee, J.H., Kang, G.B., Kim, S.H., Im, Y.J., Lee, D.-S., Eom, S.H.
Proteins