CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Phosphoribosylaminoimidazole-succinocarboxamide synthase

Enzyme Information

6.3.2.6
Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
based on mapping to UniProt P0A7D7
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate.
-!- Forms part of the purine biosynthesis pathway.

UniProtKB Entries (1)

P0A7D7
PUR7_ECOLI
Escherichia coli K-12
Phosphoribosylaminoimidazole-succinocarboxamide synthase

PDB Structure

PDB 2GQS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Nucleotide Complexes of Escherichia coli Phosphoribosylaminoimidazole Succinocarboxamide Synthetase.
Ginder, N.D., Binkowski, D.J., Fromm, H.J., Honzatko, R.B.
J.Biol.Chem.