CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.1150 | ACT-like. Chain A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | ACT-like. Chain A, domain 2 |
| Functional Family | Acetolactate synthase small subunit |
Enzyme Information
| 2.2.1.6 |
Acetolactate synthase.
based on mapping to UniProt Q9WZ19
2 pyruvate = 2-acetolactate + CO(2).
-!- The reaction shown is in the pathway of biosynthesis of valine. -!- The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine. -!- Formerly EC 4.1.3.18.
|
UniProtKB Entries (1)
| Q9WZ19 |
Q9WZ19_THEMA
Thermotoga maritima MSB8
Acetolactate synthase small subunit
|
PDB Structure
| PDB | 2FGC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit.
Protein Sci.
|