CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate/ornithine carbamoyltransferase
Functional Family Ornithine carbamoyltransferase, catabolic

Enzyme Information

2.1.3.3
Ornithine carbamoyltransferase.
based on mapping to UniProt Q5SJ15
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
-!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.

UniProtKB Entries (1)

Q5SJ15
Q5SJ15_THET8
Thermus thermophilus HB8
Ornithine carbamoyltransferase

PDB Structure

PDB 2EF0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of ornithine carbamoyltransferase from thermus thermophilus
Karthe, P., Kumarevel, T.S., Kuramitsu, S., Yokoyama, S.
To be Published