CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.260
Functional Family Aspartokinase LysC beta subunit

Enzyme Information

2.7.2.4
Aspartate kinase.
based on mapping to UniProt P26512
ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
-!- The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3. -!- This is also the case for two of the four isoenzymes in Arabidopsis thaliana. -!- The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.

UniProtKB Entries (1)

P26512
AK_CORGL
Corynebacterium glutamicum ATCC 13032
Aspartokinase

PDB Structure

PDB 2DTJ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Insight into Concerted Inhibition of alpha(2)beta(2)-Type Aspartate Kinase from Corynebacterium glutamicum
Yoshida, A., Tomita, T., Kurihara, T., Fushinobu, S., Kuzuyama, T., Nishiyama, M.
J.Mol.Biol.