CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.287 | Helix Hairpins | |
1.10.287.10 | S15/NS1, RNA-binding |
Domain Context
CATH Clusters
Superfamily | S15/NS1, RNA-binding |
Functional Family | Methionine--tRNA ligase, cytoplasmic |
Enzyme Information
6.1.1.10 |
Methionine--tRNA ligase.
based on mapping to UniProt P56192
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
-!- In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
|
UniProtKB Entries (1)
P56192 |
SYMC_HUMAN
Homo sapiens
Methionine--tRNA ligase, cytoplasmic
|
PDB Structure
PDB | 2DJV |
External Links | |
Method | SOLUTION NMR |
Organism | |
Primary Citation |
Solution structures of the WHEP-TRS domain of human methionyl-tRNA synthetase
To be Published
|