CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.330 | RRM (RNA recognition motif) domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.70.330 |
| Functional Family | Poly [ADP-ribose] polymerase 10 |
Enzyme Information
| 2.4.2.30 |
NAD(+) ADP-ribosyltransferase.
based on mapping to UniProt Q53GL7
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D- ribosyl)(n+1)-acceptor.
-!- The ADP-D-ribosyl group of NAD(+) is transferred to an acceptor carboxy group on a histone or the enzyme itself, and further ADP- ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.
|
UniProtKB Entries (1)
| Q53GL7 |
PAR10_HUMAN
Homo sapiens
Poly [ADP-ribose] polymerase 10
|
PDB Structure
| PDB | 2DHX |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution Structure of the RRM Domain in the Human Poly (ADP-ribose) Polymerase Family, Member 10 Variant
To be Published
|
