CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family 5,10-methenyltetrahydromethanopterin hydrogenase

Enzyme Information

1.12.98.2
5,10-methenyltetrahydromethanopterin hydrogenase.
based on mapping to UniProt Q58194
H(2) + 5,10-methenyltetrahydromethanopterin = H(+) + 5,10- methylenetetrahydromethanopterin.
-!- Does not catalyze the reduction of artificial dyes. -!- Does not by itself catalyze a H(2)/H(+) exchange reaction. -!- Does not contain nickel or iron-sulfur clusters. -!- Formerly EC 1.12.99.4.

UniProtKB Entries (1)

Q58194
HMD_METJA
Methanocaldococcus jannaschii DSM 2661
5,10-methenyltetrahydromethanopterin hydrogenase

PDB Structure

PDB 2B0J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Crystal Structure of the Apoenzyme of the Iron-Sulphur Cluster-free Hydrogenase
Pilak, O., Mamat, B., Vogt, S., Hagemeier, C.H., Thauer, R.K., Shima, S., Vonrhein, C., Warkentin, E., Ermler, U.
J.Mol.Biol.