CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Probable trans-2-enoyl-CoA reductase, mitochondrial

Enzyme Information

1.3.1.38
Trans-2-enoyl-CoA reductase (NADPH).
based on mapping to UniProt Q9BV79
Acyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.
-!- Not identical with EC 1.3.1.37 (cf. EC 1.3.1.8).

UniProtKB Entries (1)

Q9BV79
MECR_HUMAN
Homo sapiens
Trans-2-enoyl-CoA reductase, mitochondrial

PDB Structure

PDB 1ZSY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of human mitochondrial 2-enoyl thioester reductase (CGI-63)
Lukacik, P., Shafqat, N., Kavanagh, K.L., Johansson, C., Smee, C., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Oppermann, U.
To be Published